Drug design with Cdc7 kinase: a potential novel cancer therapy target

Por Sawa, Masaaki, Masai, Hisao
Publicado em 2009

A Novel Aminotetralin-Type Serotonin (5-HT) (2C) Receptor-Specific Agonist and 5-HT(2A) Competitive...

Por Canal, Clinton E., Morgan, Drake, Felsing, Daniel, Kondabolu, Krishnakanth, Rowland, Neil E., Robertson, Kimberly L., Sakhuja, Rajeev, Booth, Raymond G.
Publicado em 2014

The novel Bcl-2 inhibitor ABT-737 is more effective in hypoxia, and is able to reverse hypoxia-induced drug resistance in neuroblastoma cells

Por Klymenko, Tetyana, Brandenburg, Martin, Morrow, Christopher, Dive, Caroline, Makin, Guy
Publicado em 2011

Does ‘Strong Analgesic’ Equal ‘Strong Opioid’? Tapentadol and the Concept of ‘µ-Load’

Por Raffa, Robert B., Elling, Christian, Tzschentke, Thomas M.
Publicado no Adv Ther (2018)

Novel topical therapies for distal colitis

Por Lawrance, Ian Craig
Publicado em 2010

Oligonucleotide Delivery by Nucleofection Does Not Rescue the Reduced Proliferation Phenotype of Gene-Edited Cells

Por Livingston, Paula, Strouse, Bryan, Perry, Haley, Borjigin, Mandula, Bialk, Pawel, Kmiec, Eric B.
Publicado em 2012

A review of studies of adherence with antihypertensive drugs using prescription databases

Por Fitz-Simon, Nicola, Bennett, Kathleen, Feely, John
Publicado em 2005

Small Molecule Positive Allosteric Modulation of TRPV1 Activation by Vanilloids and Acidic pH

Por Kaszas, Krisztian, Keller, Jason M., Coddou, Claudio, Mishra, Santosh K., Hoon, Mark A., Stojilkovic, Stanko, Jacobson, Kenneth A., Iadarola, Michael J.
Publicado em 2012

Analgesic Properties of a Peripherally Acting and GalR2 Receptor–Preferring Galanin Analog in Inflammatory, Neuropathic, and Acute Pain Models

Por Metcalf, Cameron S., Klein, Brian D., McDougle, Daniel R., Zhang, Liuyin, Smith, Misty D., Bulaj, Grzegorz, White, H. Steve
Publicado no J Pharmacol Exp Ther (2015)

Structure-Activity Relationships, Pharmacokinetics, and Pharmacodynamics of the Kir6.2/SUR1-Specific Channel Opener VU0071063

Por Kharade, Sujay V., Sanchez-Andres, Juan Vicente, Fulton, Mark G., Shelton, Elaine L., Blobaum, Anna L., Engers, Darren W., Hofmann, Christopher S., Dadi, Prasanna K., Lantier, Louise, Jacobson, David A., Lindsley, Craig W., Denton, Jerod S.
Publicado no J Pharmacol Exp Ther (2019)

Treatment of allergic rhinitis and urticaria: a review of the newest antihistamine drug bilastine

Por Wang, Xue Yan, Lim-Jurado, Margaret, Prepageran, Narayanan, Tantilipikorn, Pongsakorn, Wang, De Yun
Publicado no Ther Clin Risk Manag (2016)

HU-444, a Novel, Potent Anti-Inflammatory, Nonpsychotropic Cannabinoid

Por Haj, Christeene G., Sumariwalla, Percy F., Hanuš, Lumír, Kogan, Natalya M., Yektin, Zhana, Mechoulam, Raphael, Feldmann, Mark, Gallily, Ruth
Publicado no J Pharmacol Exp Ther (2015)

Eremomycin pyrrolidide: a novel semisynthetic glycopeptide with improved chemotherapeutic properties

Por Olsufyeva, Evgenia N, Shchekotikhin, Andrey E, Bychkova, Elena N, Pereverzeva, Eleonora R, Treshalin, Ivan D, Mirchink, Elena P, Isakova, Elena B, Chernobrovkin, Mikhail G, Kozlov, Roman S, Dekhnich, Andrey V, Preobrazhenskaya, Maria N
Publicado no Drug Des Devel Ther (2018)

Development of Novel Small Hairpin RNAs That do not Require Processing by Dicer or AGO2

Por Ohno, Shin-ichiro, Itano, Karen, Harada, Yuichirou, Asada, Koutaro, Oikawa, Keiki, Kashiwazako, Mikie, Okuyama, Hikaru, Kumagai, Katsuyoshi, Takanashi, Masakatsu, Sudo, Katsuko, Ikeda, Norihiko, Kuroda, Masahiko
Publicado no Mol Ther (2016)

Kappa Opioid Receptor-Mediated Disruption of Novel Object Recognition: Relevance for Psychostimulant Treatment

Por Paris, Jason J., Reilley, Kate J., McLaughlin, Jay P.
Publicado em 2011

Cobinamides Are Novel Coactivators of Nitric Oxide Receptor That Target Soluble Guanylyl Cyclase Catalytic Domain

Por Sharina, Iraida, Sobolevsky, Michael, Doursout, Marie-Francoise, Gryko, Dorota, Martin, Emil
Publicado em 2012

Novel curcumin-loaded human serum albumin nanoparticles surface functionalized with folate: characterization and in vitro/vivo evaluation

Por Song, Zhiwang, Lu, Yonglin, Zhang, Xia, Wang, Haiping, Han, Junyi, Dong, Chunyan
Publicado no Drug Des Devel Ther (2016)

Combined isosorbide dinitrate and ibuprofen as a novel therapy for muscular dystrophies: evidence from Phase I studies in healthy volunteers

Por Cossu, Maria Vittoria, Cattaneo, Dario, Fucile, Serena, Pellegrino, Paolo, Baldelli, Sara, Cozzi, Valeria, Capetti, Amedeo, Clementi, Emilio
Publicado em 2014

A novel combination: ranpirnase and rosiglitazone induce a synergistic apoptotic effect by down-regulating Fra-1 and Survivin in cancer cells

Por Ramos-Nino, Maria E, Littenberg, Benjamin
Publicado em 2008

A novel sulindac derivative inhibits lung adenocarcinoma cell growth through suppression of Akt/mTOR signaling and induction of autophagy

Por Gurpinar, Evrim, Grizzle, William E., Shacka, John J., Mader, Burton J., Li, Nan, Piazza, Nicholas A., Russo, Suzanne, Keeton, Adam B., Piazza, Gary A.
Publicado em 2013