Development of Novel Small Hairpin RNAs That do not Require Processing by Dicer or AGO2

The innate cytokine response to nucleic acid is the most challenging problem confronting the practical use of nucleic acid medicine. The degree of stimulation of the innate cytokine response strongly depends on the length of the nucleic acid. In this study, we developed a 30-nucleotide single-strand...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Ohno, Shin-ichiro, Itano, Karen, Harada, Yuichirou, Asada, Koutaro, Oikawa, Keiki, Kashiwazako, Mikie, Okuyama, Hikaru, Kumagai, Katsuyoshi, Takanashi, Masakatsu, Sudo, Katsuko, Ikeda, Norihiko, Kuroda, Masahiko
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5088761/
https://ncbi.nlm.nih.gov/pubmed/27109632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2016.81
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