Development of Novel Small Hairpin RNAs That do not Require Processing by Dicer or AGO2

The innate cytokine response to nucleic acid is the most challenging problem confronting the practical use of nucleic acid medicine. The degree of stimulation of the innate cytokine response strongly depends on the length of the nucleic acid. In this study, we developed a 30-nucleotide single-strand...

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Detalles Bibliográficos
Publicado en:Mol Ther
Autores principales: Ohno, Shin-ichiro, Itano, Karen, Harada, Yuichirou, Asada, Koutaro, Oikawa, Keiki, Kashiwazako, Mikie, Okuyama, Hikaru, Kumagai, Katsuyoshi, Takanashi, Masakatsu, Sudo, Katsuko, Ikeda, Norihiko, Kuroda, Masahiko
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2016
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5088761/
https://ncbi.nlm.nih.gov/pubmed/27109632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2016.81
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