The novel Bcl-2 inhibitor ABT-737 is more effective in hypoxia, and is able to reverse hypoxia-induced drug resistance in neuroblastoma cells

door Klymenko, Tetyana, Brandenburg, Martin, Morrow, Christopher, Dive, Caroline, Makin, Guy
Gepubliceerd in 2011

Nucleocytoplasmic shuttling by nucleoporins Nup153 and Nup214 and CRM1-dependent nuclear export control the subcellular distribution of latent Stat1

door Marg, Andreas, Shan, Ying, Meyer, Thomas, Meissner, Torsten, Brandenburg, Martin, Vinkemeier, Uwe
Gepubliceerd in 2004

Hypoxic human cancer cells are sensitized to BH-3 mimetic–induced apoptosis via downregulation of the Bcl-2 protein Mcl-1

door Harrison, Luke R.E., Micha, Dimitra, Brandenburg, Martin, Simpson, Kathryn L., Morrow, Christopher J., Denneny, Olive, Hodgkinson, Cassandra, Yunus, Zaira, Dempsey, Clare, Roberts, Darren, Blackhall, Fiona, Makin, Guy, Dive, Caroline
Gepubliceerd in 2011

Phosphorylation of Tip60 by GSK-3 determines the induction of PUMA and apoptosis by p53

door Charvet, Céline, Wissler, Manuela, Brauns-Schubert, Prisca, Wang, Shang-Jui, Tang, Yi, Sigloch, Florian C., Mellert, Hestia, Brandenburg, Martin, Lindner, Silke E., Breit, Bernhard, Green, Douglas R., McMahon, Steven B., Borner, Christoph, Gu, Wei, Maurer, Ulrich
Gepubliceerd in 2011