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Small Molecule Positive Allosteric Modulation of TRPV1 Activation by Vanilloids and Acidic pH
Transient receptor potential cation channel subfamily V member 1 (TRPV1) is a high-conductance, nonselective cation channel strongly expressed in nociceptive primary afferent neurons of the peripheral nervous system and functions as a multimodal nociceptor gated by temperatures greater than 43°C, pr...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3251023/ https://ncbi.nlm.nih.gov/pubmed/22005042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.183053 |
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