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Conserved allosteric pathways for activation of TRPV3 revealed through engineering vanilloid-sensitivity

The Transient Receptor Potential Vanilloid 1 (TRPV) channel is activated by an array of stimuli, including heat and vanilloid compounds. The TRPV1 homologues TRPV2 and TRPV3 are also activated by heat, but sensitivity to vanilloids and many other agonists is not conserved among TRPV subfamily member...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:eLife
मुख्य लेखकों: Zhang, Feng, Swartz, Kenton Jon, Jara-Oseguera, Andres
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: eLife Sciences Publications, Ltd 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6333442/
https://ncbi.nlm.nih.gov/pubmed/30644819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.42756
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