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Analgesic Properties of a Peripherally Acting and GalR2 Receptor–Preferring Galanin Analog in Inflammatory, Neuropathic, and Acute Pain Models

There are ongoing efforts to develop pain therapeutics with novel mechanisms of action that avoid common side effects associated with other analgesics. The anticonvulsant neuropeptide galanin is a potent regulator of neuronal excitability and has a well established role in pain modulation, making it...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Metcalf, Cameron S., Klein, Brian D., McDougle, Daniel R., Zhang, Liuyin, Smith, Misty D., Bulaj, Grzegorz, White, H. Steve
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279104/
https://ncbi.nlm.nih.gov/pubmed/25347995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.114.219063
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