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Generating Orally-Active Galanin Analogs with Analgesic Activities
The endogenous neuropeptide galanin has anticonvulsant and analgesic properties mediated by galanin receptors expressed in the central and peripheral nervous systems. Our previous work showed that combination of truncation of the galanin peptide along with N-and C-terminal modifications afforded ana...
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| Publié dans: | ChemMedChem |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4332549/ https://ncbi.nlm.nih.gov/pubmed/22374865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201100574 |
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