Developing novel antiepileptic drugs: Characterization of NAX 5055, a systemically-active galanin analog, in epilepsy models

The endogenous neuropeptide galanin and its associated receptors galanin receptor 1 and galanin receptor 2 are highly localized in brain limbic structures and play an important role in the control of seizures in animal epilepsy models. As such, galanin receptors provide an attractive target for the...

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Publicat a:Neurotherapeutics
Autors principals: White, H. Steve, Scholl, Erika A., Klein, Brian D., Flynn, Sean P., Pruess, Timothy H., Green, Brad R., Zhang, Liuyin, Bulaj, Grzegorz
Format: Artigo
Idioma:Inglês
Publicat: Springer-Verlag 2009
Matèries:
Theme 4: Novel Delivery Approach
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402707/
https://ncbi.nlm.nih.gov/pubmed/19332332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nurt.2009.01.001
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