Developing novel antiepileptic drugs: Characterization of NAX 5055, a systemically-active galanin analog, in epilepsy models

The endogenous neuropeptide galanin and its associated receptors galanin receptor 1 and galanin receptor 2 are highly localized in brain limbic structures and play an important role in the control of seizures in animal epilepsy models. As such, galanin receptors provide an attractive target for the...

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Dettagli Bibliografici
Pubblicato in:Neurotherapeutics
Autori principali: White, H. Steve, Scholl, Erika A., Klein, Brian D., Flynn, Sean P., Pruess, Timothy H., Green, Brad R., Zhang, Liuyin, Bulaj, Grzegorz
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer-Verlag 2009
Soggetti:
Theme 4: Novel Delivery Approach
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402707/
https://ncbi.nlm.nih.gov/pubmed/19332332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nurt.2009.01.001
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