Structure and function of μ-conotoxins, peptide-based sodium channel blockers with analgesic activity

par Green, Brad R, Bulaj, Grzegorz, Norton, Raymond S
Publié dans Future Med Chem (2014)

Analgesic Neuropeptide W Suppresses Seizures in the Brain Revealed by Rational Repositioning and Peptide Engineering

par Green, Brad R., Smith, Misty, White, Karen L., White, H. Steve, Bulaj, Grzegorz
Publié 2010

Structural Requirements for a Lipoamino Acid in Modulating the Anticonvulsant Activities of the Systemically-Active Galanin Analogs

par Zhang, Liuyin, Robertson, Charles R., Green, Brad R., Pruess, Timothy H., White, H. Steve, Bulaj, Grzegorz
Publié 2009

Engineering Galanin Analogues that Discriminate Between GalR1 and GalR2 Receptor Subtypes and Exhibit Anticonvulsant Activity Following Systemic Delivery

par Robertson, Charles R., Scholl, Erika Adkins, Pruess, Timothy H., Green, Brad R., White, H. Steve, Bulaj, Grzegorz
Publié 2010

Developing novel antiepileptic drugs: Characterization of NAX 5055, a systemically-active galanin analog, in epilepsy models

par White, H. Steve, Scholl, Erika A., Klein, Brian D., Flynn, Sean P., Pruess, Timothy H., Green, Brad R., Zhang, Liuyin, Bulaj, Grzegorz
Publié dans Neurotherapeutics (2009)

Stapling Mimics Noncovalent Interactions of γ-Carboxyglutamates in Conantokins, Peptidic Antagonists of N-Methyl-d-Aspartic Acid Receptors

par Platt, Randall J., Han, Tiffany S., Green, Brad R., Smith, Misty D., Skalicky, Jack, Gruszczyński, Paweł, White, H. Steve, Olivera, Baldomero, Bulaj, Grzegorz, Gajewiak, Joanna
Publié 2012

Distinct disulfide isomers of μ-conotoxins KIIIA and KIIIB block voltage-gated sodium channels

par Khoo, Keith K., Gupta, Kallol, Green, Brad R., Zhang, Min-Min, Watkins, Maren, Olivera, Baldomero M., Balaram, Padmanabhan, Yoshikami, Doju, Bulaj, Grzegorz, Norton, Raymond S.
Publié 2012

Pruning Nature: Biodiversity-Derived Discovery of Novel Sodium Channel Blocking Conotoxins from Conus bullatus

par Holford, Mandë, Zhang, Min-Min, Gowd, K. Hanumae, Azam, Layla, Green, Brad R., Watkins, Maren, Ownby, John-Paul, Yoshikami, Doju, Bulaj, Grzegorz, Olivera, Baldomero M.
Publié 2008

Interactions of Disulfide-deficient Selenocysteine Analogs of μ-Conotoxin BuIIIB with the Voltage-Gated Sodium Channel Na(V)1.3

par Green, Brad R., Zhang, Min-Min, Chhabra, Sandeep, Robinson, Samuel D., Wilson, Michael J., Redding, Addison, Olivera, Baldomero M., Yoshikami, Doju, Bulaj, Grzegorz, Norton, Raymond S.
Publié 2014

Structural Basis for the Inhibition of Voltage-gated Sodium Channels by Conotoxin μO§-GVIIJ

par Green, Brad R., Gajewiak, Joanna, Chhabra, Sandeep, Skalicky, Jack J., Zhang, Min-Min, Rivier, Jean E., Bulaj, Grzegorz, Olivera, Baldomero M., Yoshikami, Doju, Norton, Raymond S.
Publié dans J Biol Chem (2016)

Improving the Clinical Skills Performance of Graduating Medical Students Using “WISE OnCall,” a Multimedia Educational Module

par Szyld, Demian, Uquillas, Kristen, Green, Brad R., Yavner, Steven D., Song, Hyuksoon, Nick, Michael W., Ng, Grace M., Pusic, Martin V., Riles, Thomas S., Kalet, Adina
Publié dans Simul Healthc (2017)

A disulfide tether stabilizes the block of sodium channels by the conotoxin μO§-GVIIJ

par Gajewiak, Joanna, Azam, Layla, Imperial, Julita, Walewska, Aleksandra, Green, Brad R., Bandyopadhyay, Pradip K., Raghuraman, Shrinivasan, Ueberheide, Beatrix, Bern, Marshall, Zhou, H. Mimi, Minassian, Natali A., Hagan, Rebecca H., Flinspach, Mack, Liu, Yi, Bulaj, Grzegorz, Wickenden, Alan D., Olivera, Baldomero M., Yoshikami, Doju, Zhang, Min-Min
Publié 2014