Alpha-conotoxins as pharmacological probes of nicotinic acetylcholine receptors

per Azam, Layla, McIntosh, J Michael
Publicat 2009

Molecular basis for the differential sensitivity of rat and human α9α10 nAChRs to α-conotoxin RgIA

per Azam, Layla, McIntosh, J Michael
Publicat 2012

Developmental regulation of nicotinic acetylcholine receptors within midbrain dopamine neurons

per Azam, Layla, Chen, Yiling, Leslie, Frances M.
Publicat 2006

Amino Acid Residues That Confer High Selectivity of the α6 Nicotinic Acetylcholine Receptor Subunit to α-Conotoxin MII[S4A,E11A,L15A]

per Azam, Layla, Yoshikami, Doju, McIntosh, J. Michael
Publicat 2008

Na(V)β Subunits Modulate the Inhibition of Na(V)1.8 by the Analgesic Gating Modifier μO-Conotoxin MrVIB

per Wilson, Michael J., Zhang, Min-Min, Azam, Layla, Olivera, Baldomero M., Bulaj, Grzegorz, Yoshikami, Doju
Publicat 2011

Structure, dynamics and selectivity of the sodium channel blocker µ-conotoxin SIIIA,

per Yao, Shenggen, Zhang, Minmin, Yoshikami, Doju, Azam, Layla, Olivera, Baldomero M., Bulaj, Grzegorz, Norton, Raymond S.
Publicat 2008

Molecular Interaction of α-Conotoxin RgIA with the Rat α9α10 Nicotinic Acetylcholine Receptor

per Azam, Layla, Papakyriakou, Athanasios, Zouridakis, Marios, Giastas, Petros, Tzartos, Socrates J., McIntosh, J. Michael
Publicat a Mol Pharmacol (2015)

μ-Conotoxins that differentially block sodium channels Na(V)1.1 through 1.8 identify those responsible for action potentials in sciatic nerve

per Wilson, Michael J., Yoshikami, Doju, Azam, Layla, Gajewiak, Joanna, Olivera, Baldomero M., Bulaj, Grzegorz, Zhang, Min-Min
Publicat 2011

Specificity, affinity and efficacy of iota-conotoxin RXIA, an agonist of voltage-gated sodium channels Na(V)1.2, 1.6 and 1.7

per Fiedler, Brian, Zhang, Min-Min, Buczek, Oga, Azam, Layla, Bulaj, Grzegorz, Norton, Raymond S, Olivera, Baldomero M, Yoshikami, Doju
Publicat 2008

Positional Scanning Mutagenesis of α-Conotoxin PeIA Identifies Critical Residues That Confer Potency and Selectivity for α6/α3β2β3 and α3β2 Nicotinic Acetylcholine Receptors

per Hone, Arik J., Ruiz, Miguel, Scadden, Mick'l, Christensen, Sean, Gajewiak, Joanna, Azam, Layla, McIntosh, J. Michael
Publicat 2013

α- And β-subunit composition of voltage-gated sodium channels investigated with μ-conotoxins and the recently discovered μO§-conotoxin GVIIJ

per Wilson, Michael J., Zhang, Min-Min, Gajewiak, Joanna, Azam, Layla, Rivier, Jean E., Olivera, Baldomero M., Yoshikami, Doju
Publicat a J Neurophysiol (2015)

Synergistic and Antagonistic Interactions between Tetrodotoxin and μ-Conotoxin in Blocking Voltage-gated Sodium Channels

per Zhang, Min-Min, McArthur, Jeff R., Azam, Layla, Bulaj, Grzegorz, Olivera, Baldomero M, French, Robert J, Yoshikami, Doju
Publicat 2009

α-Conotoxin BuIA[T5A;P6O]: a novel ligand that discriminates between α6β4 and α6β2 nicotinic acetylcholine receptors and blocks nicotine-stimulated norepinephrine release

per Azam, Layla, Maskos, Uwe, Changeux, Jean-Pierre, Dowell, Cheryl D., Christensen, Sean, De Biasi, Mariella, McIntosh, J. Michael
Publicat 2010

Co-expression of Na(V)β subunits alters the kinetics of inhibition of voltage-gated sodium channels by pore-blocking μ-conotoxins

per Zhang, Min-Min, Wilson, Michael J, Azam, Layla, Gajewiak, Joanna, Rivier, Jean E, Bulaj, Grzegorz, Olivera, Baldomero M, Yoshikami, Doju
Publicat 2013

α-Conotoxins Identify the α3β4* Subtype as the Predominant Nicotinic Acetylcholine Receptor Expressed in Human Adrenal Chromaffin Cells

per Hone, Arik J., McIntosh, J. Michael, Azam, Layla, Lindstrom, Jon, Lucero, Linda, Whiteaker, Paul, Passas, Juan, Blázquez, Jesús, Albillos, Almudena
Publicat a Mol Pharmacol (2015)

αM-Conotoxin MIIIJ Blocks Nicotinic Acetylcholine Receptors at Neuromuscular Junctions of Frog and Fish

per Rybin, Matthew J., O’Brien, Henrik, Ramiro, Iris Bea L., Azam, Layla, McIntosh, J. Michael, Olivera, Baldomero M., Safavi-Hemami, Helena, Yoshikami, Doju
Publicat a Toxins (Basel) (2020)

Pruning Nature: Biodiversity-Derived Discovery of Novel Sodium Channel Blocking Conotoxins from Conus bullatus

per Holford, Mandë, Zhang, Min-Min, Gowd, K. Hanumae, Azam, Layla, Green, Brad R., Watkins, Maren, Ownby, John-Paul, Yoshikami, Doju, Bulaj, Grzegorz, Olivera, Baldomero M.
Publicat 2008

A disulfide tether stabilizes the block of sodium channels by the conotoxin μO§-GVIIJ

per Gajewiak, Joanna, Azam, Layla, Imperial, Julita, Walewska, Aleksandra, Green, Brad R., Bandyopadhyay, Pradip K., Raghuraman, Shrinivasan, Ueberheide, Beatrix, Bern, Marshall, Zhou, H. Mimi, Minassian, Natali A., Hagan, Rebecca H., Flinspach, Mack, Liu, Yi, Bulaj, Grzegorz, Wickenden, Alan D., Olivera, Baldomero M., Yoshikami, Doju, Zhang, Min-Min
Publicat 2014