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Generating Orally-Active Galanin Analogs with Analgesic Activities

The endogenous neuropeptide galanin has anticonvulsant and analgesic properties mediated by galanin receptors expressed in the central and peripheral nervous systems. Our previous work showed that combination of truncation of the galanin peptide along with N-and C-terminal modifications afforded ana...

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Publicat a:ChemMedChem
Autors principals: Robertson, Charles R., Pruess, Timothy H., Grussendorf, Erin, White, H. Steve, Bulaj, Grzegorz
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332549/
https://ncbi.nlm.nih.gov/pubmed/22374865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201100574
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