Endocannabinoids Anandamide and 2-Arachidonoylglycerol Are Substrates for Human CYP2J2 Epoxygenase

Por McDougle, Daniel R., Kambalyal, Amogh, Meling, Daryl D., Das, Aditi
Publicado no J Pharmacol Exp Ther (2014)

Functional studies of N-terminally modified CYP2J2 epoxygenase in model lipid bilayers

Por McDougle, Daniel R, Palaria, Amrita, Magnetta, Eric, Meling, Daryl D, Das, Aditi
Publicado em 2013

Preclinical analgesic and safety evaluation of the GalR2-preferring analog, NAX 810-2

Por Metcalf, Cameron S., Smith, Misty D., Klein, Brian D., McDougle, Daniel R., Zhang, Liuyin, Bulaj, Grzegorz
Publicado no Neurochem Res (2017)

Pre-Clinical Evaluation of Intravenous NAX 810-2, a Novel GalR2-Preferring Analog, for Anticonvulsant Efficacy and Pharmacokinetics

Por Metcalf, Cameron S., Klein, Brian D., McDougle, Daniel R., Zhang, Liuyin, Kaufmann, Dan, Bulaj, Grzegorz, White, H. Steve
Publicado no Epilepsia (2017)

Analgesic Properties of a Peripherally Acting and GalR2 Receptor–Preferring Galanin Analog in Inflammatory, Neuropathic, and Acute Pain Models

Por Metcalf, Cameron S., Klein, Brian D., McDougle, Daniel R., Zhang, Liuyin, Smith, Misty D., Bulaj, Grzegorz, White, H. Steve
Publicado no J Pharmacol Exp Ther (2015)

Granulosa cell endothelin-2 expression is fundamental for ovulatory follicle rupture

Por Cacioppo, Joseph A., Lin, Po-Ching Patrick, Hannon, Patrick R., McDougle, Daniel R., Gal, Arnon, Ko, CheMyong
Publicado no Sci Rep (2017)

Incorporation of Charged Residues in the CYP2J2 F-G Loop Disrupts CYP2J2-Lipid Bilayer Interactions

Por McDougle, Daniel R., Baylon, Javier L., Meling, Daryl D., Kambalyal, Amogh, Grinkova, Yelena V., Hammernik, Jared, Tajkhorshid, Emad, Das, Aditi
Publicado no Biochim Biophys Acta (2015)

CYCLOOXYGENASE-2 CATALYSIS AND INHIBITION IN LIPID BILAYER NANODISCS

Por Orlando, Benjamin J., McDougle, Daniel R., Lucido, Michael J., Eng, Edward T., Graham, Leigh Ann, Schneider, Claus, Stokes, David L., Das, Aditi, Malkowski, Michael G.
Publicado em 2014

Anti-inflammatory ω-3 endocannabinoid epoxides

Por McDougle, Daniel R., Watson, Josephine E., Abdeen, Amr A., Adili, Reheman, Caputo, Megan P., Krapf, John E., Johnson, Rodney W., Kilian, Kristopher A., Holinstat, Michael, Das, Aditi
Publicado no Proc Natl Acad Sci U S A (2017)