The serotonin 5-HT(2C) receptor and the non-addictive nature of classic hallucinogens

Por Canal, Clinton E, Murnane, Kevin S
Publicado no J Psychopharmacol (2016)

Classics in Chemical Neuroscience: Aripiprazole

Por Casey, Austen B., Canal, Clinton E.
Publicado no ACS Chem Neurosci (2017)

Amnesia produced by altered release of neurotransmitters after intraamygdala injections of a protein synthesis inhibitor

Por Canal, Clinton E., Chang, Qing, Gold, Paul E.
Publicado em 2007

Intra-amygdala injections of CREB antisense impair inhibitory avoidance memory: Role of norepinephrine and acetylcholine

Por Canal, Clinton E., Chang, Qing, Gold, Paul E.
Publicado em 2008

Support for 5-HT2C receptor functional selectivity in vivo utilizing structurally diverse, selective 5-HT2C receptor ligands and the 2,5-dimethoxy-4-iodoamphetamine elicited head-t...

Por Canal, Clinton E., Booth, Raymond G., Morgan, Drake
Publicado em 2013

Glucose injections into the dorsal hippocampus or dorsolateral striatum of rats prior to T-maze training: Modulation of learning rates and strategy selection

Por Canal, Clinton E., Stutz, Sonja J., Gold, Paul E.
Publicado em 2005

Molecular Determinants for Ligand Binding at Serotonin 5-HT(2A) and 5-HT(2C) GPCRs: Experimental Affinity Results Analyzed by Molecular Modeling and Ligand Docking Studies

Por Córdova-Sintjago, Tania, Sakhuja, Rajeev, Kondabolu, Krishnakanth, Canal, Clinton E., Booth, Raymond G.
Publicado em 2012

RNA editing of the serotonin 2C receptor and expression of Gα(q) protein: genetic mouse models do not support a role for regulation or compensation

Por Canal, Clinton E., Mahautmr, Kontip C., Cao, Chike, Sanders-Bush, Elaine, Airey, David C.
Publicado em 2009

Molecular Pharmacology and Ligand Docking Studies Reveal a Single Amino Acid Difference between Mouse and Human Serotonin 5-HT2A Receptors That Impacts Behavioral Translation of No...

Por Canal, Clinton E., Cordova-Sintjago, Tania, Liu, Yue, Kim, Myong S., Morgan, Drake, Booth, Raymond G.
Publicado em 2013

Drug discovery targeting human 5-HT(2C) receptors: Residues S3.36 and Y7.43 impact ligand—binding pocket structure via hydrogen bond formation

Por Canal, Clinton E., Cordova-Sintjago, Tania C., Villa, Nancy Y., Fang, Li-Juan, Booth, Raymond G.
Publicado em 2011

Impact of RNA Editing on Functions of the Serotonin 2C Receptor in vivo

Por Olaghere da Silva, Uade B., Morabito, Michael V., Canal, Clinton E., Airey, David C., Emeson, Ronald B., Sanders-Bush, Elaine
Publicado em 2010

The serotonin 2C receptor potently modulates the head-twitch response in mice induced by a phenethylamine hallucinogen

Por Canal, Clinton E., Olaghere da Silva, Uade B., Gresch, Paul J., Watt, Erin E., Sanders-Bush, Elaine, Airey, David C.
Publicado em 2010

A Novel Aminotetralin-Type Serotonin (5-HT) (2C) Receptor-Specific Agonist and 5-HT(2A) Competitive Antagonist/5-HT(2B) Inverse Agonist with Preclinical Efficacy for Psychoses

Por Canal, Clinton E., Morgan, Drake, Felsing, Daniel, Kondabolu, Krishnakanth, Rowland, Neil E., Robertson, Kimberly L., Sakhuja, Rajeev, Booth, Raymond G.
Publicado em 2014

Novel 4-Substituted-N,N-dimethyltetrahydronaphthalen-2-amines: Synthesis, Affinity, and In Silico Docking Studies at Serotonin 5-HT2-type and Histamine H(1) G Protein-Coupled Recep...

Por Sakhuja, Rajeev, Kondabolu, Krishnakanth, Córdova-Sintjago, Tania, Travers, Sean, Vincek, Adam S., Kim, Myong Sang, Abboud, Khalil A., Fang, Lijuan, Sun, Zhuming, Canal, Clinton E., Booth, Raymond G.
Publicado no Bioorg Med Chem (2015)