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Does ‘Strong Analgesic’ Equal ‘Strong Opioid’? Tapentadol and the Concept of ‘µ-Load’

INTRODUCTION: The distinct properties of the centrally-acting analgesic tapentadol derive from the combined contributions of an opioid component and a nonopioid component. However, the opioid component’s relative contribution to analgesic and adverse effects has not previously been elucidated. Tapen...

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Detalhes bibliográficos
Publicado no:Adv Ther
Main Authors: Raffa, Robert B., Elling, Christian, Tzschentke, Thomas M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Healthcare 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6182641/
https://ncbi.nlm.nih.gov/pubmed/30206823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12325-018-0778-x
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