Pesquisas alternativas:
doses develop » loss develop (Expandir a Pesquisa), models develop (Expandir a Pesquisa), locus develop (Expandir a Pesquisa)
develop type » developing type (Expandir a Pesquisa)
dna develop » a develop (Expandir a Pesquisa), 133a develop (Expandir a Pesquisa), cd38 develop (Expandir a Pesquisa)
drug doses » drug dose (Expandir a Pesquisa), drug disease (Expandir a Pesquisa)
doses develop » loss develop (Expandir a Pesquisa), models develop (Expandir a Pesquisa), locus develop (Expandir a Pesquisa)
develop type » developing type (Expandir a Pesquisa)
dna develop » a develop (Expandir a Pesquisa), 133a develop (Expandir a Pesquisa), cd38 develop (Expandir a Pesquisa)
drug doses » drug dose (Expandir a Pesquisa), drug disease (Expandir a Pesquisa)
1
“... delay and clonogenic cell survival during repeated drug treatment. A slow rate of resistance development...”
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2
Por Hoffman-Luca, C. Gianna, Yang, Chao-Yie, Lu, Jianfeng, Ziazadeh, Daniel, McEachern, Donna, Debussche, Laurent, Wang, Shaomeng
Publicado no PLoS One (2015)
“... an amplified MDM2 gene and wild-type p53, we have investigated the acquired resistance mechanisms both in vitro...”Publicado no PLoS One (2015)
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3
“... dependent on the drug’s pharmacological action and dose. Common Type B reactions seen in clinical practice...”
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4
Por Carrington, Emma M., McKenzie, Mark D., Jansen, Elisa, Myers, Michelle, Fynch, Stacey, Kos, Cameron, Strasser, Andreas, Kay, Thomas W., Scott, Clare L., Allison, Janette
Publicado em 2009
“...-cells developed but were abnormally sensitive to apoptosis induced in vivo by low-dose STZ. Although a...”Publicado em 2009
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5
Por Zhang, Weiguo, Gao, Chen, Konopleva, Marina, Chen, Ye, Jacamo, Rodrigo O., Borthakur, Gautam, Cortes, Jorge E., Ravandi, Farhad, Ramachandran, Abhijit, Andreeff, Michael
Publicado em 2014
“... to increasing doses of sorafenib, and in FLT3 ITD mutated AML patients, who developed relapse following...”Publicado em 2014
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6
Por Bhattacharya, Sudin, Shoda, Lisl K.M., Zhang, Qiang, Woods, Courtney G., Howell, Brett A., Siler, Scott Q., Woodhead, Jeffrey L., Yang, Yuching, McMullen, Patrick, Watkins, Paul B., Andersen, Melvin E.
Publicado em 2012
“... of chemical- and drug-induced toxicity. The concept of “toxicity pathways” is described in the context...”Publicado em 2012
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7
8
Por Smee, Donald F., Sidwell, Robert W., Kefauver, Debbie, Bray, Mike, Huggins, John W.
Publicado em 2002
“..., the drug prevented mortality in 80 to 100% of the mice treated with a single 100-mg/kg dose at 1, 2, 3...”Publicado em 2002
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9
Por Ono, Suzane Kioko, Kato, Naoya, Shiratori, Yasushi, Kato, Jun, Goto, Tadashi, Schinazi, Raymond F., Carrilho, Flair José, Omata, Masao
Publicado em 2001
“...After receiving lamivudine for 3 years to treat chronic hepatitis B, 67–75% of patients develop B...”Publicado em 2001
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10
“... for systemic adenovirus infections rely on a nonhuman adenovirus. We established mouse adenovirus type 1 (MAV-1...”
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11
Por Mizuarai Shinji, Yamanaka Kazunori, Itadani Hiraku, Arai Tsuyoshi, Nishibata Toshihide, Hirai Hiroshi, Kotani Hidehito
Publicado em 2009-06-01
“... small molecule inhibitor significantly enhances the anti-tumor efficacy of DNA damaging agents...”Publicado em 2009-06-01
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12
Por Mizuarai, Shinji, Yamanaka, Kazunori, Itadani, Hiraku, Arai, Tsuyoshi, Nishibata, Toshihide, Hirai, Hiroshi, Kotani, Hidehito
Publicado em 2009
“... significantly enhances the anti-tumor efficacy of DNA damaging agents, specifically in p53 negative tumors...”Publicado em 2009
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13
Por Rabaaoui, Samira, Zouhiri, Fatima, Lançon, Agnès, Leh, Hervé, d'Angelo, Jean, Wattel, Eric
Publicado em 2008
“...The replication of the retrovirus human T-cell leukemia virus type 1 (HTLV-1) is linked...”Publicado em 2008
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14
15
Por Hauser, Andrea, Mugenyi, Kizito, Kabasinguzi, Rose, Bluethgen, Kerstin, Kuecherer, Claudia, Harms, Gundel, Kunz, Andrea
Publicado em 2009
“... single-dose nevirapine. Lower detection limits of drug-resistant HIV type 1 (HIV-1) variants carrying...”Publicado em 2009
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16
Por Huang, Sheng-Xiong, Feng, Zhiyang, Wang, Liyan, Galm, Ute, Wendt-Pienkowski, Evelyn, Yang, Dong, Tao, Meifeng, Coughlin, Jane M, Duan, Yanwen, Shen, Ben
Publicado em 2012
“... population. There have been continued efforts to develop new BLM analogues in the search for anticancer drugs...”Publicado em 2012
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17
“..., antioxidation, drug metabolism, DNA repair and cell proliferation. It remains unclear whether the process...”
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18
“..., antioxidation, drug metabolism, DNA repair and cell proliferation. It remains unclear whether the process...”
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19
Por Cui, Ying, Hausheer, Frederick, Beaty, Robert, Zahnow, Cynthia, Issa, Jean Pierre, Bunz, Frederick, Baylin, Stephen B.
Publicado em 2014
“..., and it was activated only by drug treatments that de-repress gene silencing by reversing DNA hypermethylation. We...”Publicado em 2014
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20
Por Ge, Jing, Prasongtanakij, Somsak, Wood, David K., Weingeist, David M., Fessler, Jessica, Navasummrit, Panida, Ruchirawat, Mathuros, Engelward, Bevin P.
Publicado no J Vis Exp (2014)
“... in the environment and produced within human cells as normal cellular metabolites. Ironically, at high doses DNA...”Publicado no J Vis Exp (2014)
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