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A Critical Dose of Doxorubicin Is Required to Alter the Gene Expression Profiles in MCF-7 Cells Acquiring Multidrug Resistance

Cellular mechanisms of multidrug resistance (MDR) are related to ABC transporters, apoptosis, antioxidation, drug metabolism, DNA repair and cell proliferation. It remains unclear whether the process of resistance development is programmable. We aimed to study gene expression profiling circumstances...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Tsou, Shang-Hsun, Chen, Tzer-Ming, Hsiao, Hui-Ting, Chen, Yen-Hui
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4312059/
https://ncbi.nlm.nih.gov/pubmed/25635866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116747
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