A Critical Dose of Doxorubicin Is Required to Alter the Gene Expression Profiles in MCF-7 Cells Acquiring Multidrug Resistance

Cellular mechanisms of multidrug resistance (MDR) are related to ABC transporters, apoptosis, antioxidation, drug metabolism, DNA repair and cell proliferation. It remains unclear whether the process of resistance development is programmable. We aimed to study gene expression profiling circumstances...

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Bibliographic Details
Published in:PLoS One
Main Authors: Tsou, Shang-Hsun, Chen, Tzer-Ming, Hsiao, Hui-Ting, Chen, Yen-Hui
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4312059/
https://ncbi.nlm.nih.gov/pubmed/25635866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116747
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