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A Critical Dose of Doxorubicin Is Required to Alter the Gene Expression Profiles in MCF-7 Cells Acquiring Multidrug Resistance

Cellular mechanisms of multidrug resistance (MDR) are related to ABC transporters, apoptosis, antioxidation, drug metabolism, DNA repair and cell proliferation. It remains unclear whether the process of resistance development is programmable. We aimed to study gene expression profiling circumstances...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Tsou, Shang-Hsun, Chen, Tzer-Ming, Hsiao, Hui-Ting, Chen, Yen-Hui
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4312059/
https://ncbi.nlm.nih.gov/pubmed/25635866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116747
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