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Cytotoxicity and reversal of multidrug resistance by tryptanthrin-derived indoloquinazolines
AIM: To evaluate the effects and elucidate the mechanisms of a series of indoloquinazolines as novel anticancer agents. METHODS: Condensation of the substituted isatoic anhydride with the substituted isatin was performed to prepare compounds 1–4, followed by adding malononitrile to prepare compounds...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4002843/ https://ncbi.nlm.nih.gov/pubmed/20139909 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2009.198 |
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