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Role of autophagy and lysosomal drug sequestration in acquired resistance to doxorubicin in MCF-7 cells

BACKGROUND: The roles and mechanisms involved in starvation-induced autophagy in mammalian cells have been extensively studied. However, less is known about the potential role for autophagy as a survival pathway in acquired drug resistance in cancer cells under nutrient-rich conditions. METHODS: We...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Guo, Baoqing, Tam, Adam, Santi, Stacey A., Parissenti, Amadeo M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5043608/
https://ncbi.nlm.nih.gov/pubmed/27687594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2790-3
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