Propranolol Sensitizes Vascular Sarcoma Cells to Doxorubicin by Altering Lysosomal Drug Sequestration and Drug Efflux

Angiosarcoma is a rare cancer of blood vessel–forming cells with a high patient mortality and few treatment options. Although chemotherapy often produces initial clinical responses, outcomes remain poor, largely due to the development of drug resistance. We previously identified a subset of doxorubi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Oncol
Egile Nagusiak: Saha, Jhuma, Kim, Jong Hyuk, Amaya, Clarissa N., Witcher, Caleb, Khammanivong, Ali, Korpela, Derek M., Brown, David R., Taylor, Josephine, Bryan, Brad A., Dickerson, Erin B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2021
Gaiak:
Oncology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7882688/
https://ncbi.nlm.nih.gov/pubmed/33598432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.614288
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