Type I Polyketide Synthases That Require Discrete Acyltransferases

Por Cheng, Yi-Qiang, Coughlin, Jane M., Lim, Si-Kyu, Shen, Ben
Publicado no Methods Enzymol (2009)

Functional Characterization of tlmK Unveiling Unstable Carbinolamide Intermediates in the Tallysomycin Biosynthetic Pathway

Por Wang, Liyan, Tao, Meifeng, Wendt-Pienkoski, Evelyn, Galm, Ute, Coughlin, Jane M., Shen, Ben
Publicado em 2009

In Vivo Manipulation of the Bleomycin Biosynthetic Gene Cluster in Streptomyces verticillus ATCC15003 Revealing New Insights into Its Biosynthetic Pathway

Por Galm, Ute, Wang, Liyan, Wendt-Pienkowski, Evelyn, Yang, Runying, Liu, Wen, Tao, Meifeng, Coughlin, Jane M., Shen, Ben
Publicado em 2008

Comparative Analysis of the Biosynthetic Gene Clusters and Pathways for Three Structurally Related Antitumor Antibiotics Bleomycin, Tallysomycin and Zorbamycin

Por Galm, Ute, Wendt-Pienkowski, Evelyn, Wang, Liyan, Huang, Sheng-Xiong, Unsin, Claudia, Tao, Meifeng, Coughlin, Jane M., Shen, Ben
Publicado em 2011

Oxazolomycin Biosynthesis in Streptomyces albus JA3453 Featuring an “Acyltransferase-less” Type I Polyketide Synthase That Incorporates Two Distinct Extender Units

Por Zhao, Chunhua, Coughlin, Jane M., Ju, Jianhua, Zhu, Dongqing, Wendt-Pienkowski, Evelyn, Zhou, Xiufen, Wang, Zhijun, Shen, Ben, Deng, Zixin
Publicado em 2010

Functional characterization of tlmH in Streptoalloteichus hindustanus E465-94 ATCC 31158 unveiling new insight into tallysomycin biosynthesis and affording a novel bleomycin analog

Por Tao, Meifeng, Wang, Liyan, Wendt-Pienkowski, Evelyn, Zhang, Ningning, Yang, Dong, Galm, Ute, Coughlin, Jane M., Xu, Zhinan, Shen, Ben
Publicado em 2009

BlmB and TlmB Provide Resistance to the Bleomycin Family of Antitumor Antibiotics by N-Acetylating Metal-Free Bleomycin, Tallysomycin, Phleomycin, and Zorbamycin

Por Coughlin, Jane M., Rudolf, Jeffrey D., Wendt-Pienkowski, Evelyn, Wang, Liyan, Unsin, Claudia, Galm, Ute, Yang, Dong, Tao, Meifeng, Shen, Ben
Publicado no Biochemistry (2014)

The Biosynthetic Gene Cluster of Zorbamycin, a Member of the Bleomycin Family of Antitumor Antibiotics, from Streptomyces flavoviridis ATCC 21892

Por Galm, Ute, Wendt-Pienkowski, Evelyn, Wang, Liyan, George, Nicholas P., Oh, Tae-Jin, Yi, Fan, Tao, Meifeng, Coughlin, Jane M., Shen, Ben
Publicado em 2008

A Designer Bleomycin with Significantly Improved DNA Cleavage Activity

Por Huang, Sheng-Xiong, Feng, Zhiyang, Wang, Liyan, Galm, Ute, Wendt-Pienkowski, Evelyn, Yang, Dong, Tao, Meifeng, Coughlin, Jane M, Duan, Yanwen, Shen, Ben
Publicado em 2012

The Glycopeptide Antitumor Antibiotic Zorbamycin from Streptomyces flavoviridis ATCC 21892: Strain Improvement and Structure Elucidation⊥

Por Wang, Liyan, Yun, Bong-Sik, George, Nicholas P., Wendt-Pienkowski, Evelyn, Galm, Ute, Oh, Tae-Jin, Coughlin, Jane M., Zhang, Guodong, Tao, Meifeng, Shen, Ben
Publicado em 2007