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BlmB and TlmB Provide Resistance to the Bleomycin Family of Antitumor Antibiotics by N-Acetylating Metal-Free Bleomycin, Tallysomycin, Phleomycin, and Zorbamycin
[Image: see text] The bleomycin (BLM) family of glycopeptide-derived antitumor antibiotics consists of BLMs, tallysomycins (TLMs), phleomycins (PLMs), and zorbamycin (ZBM). The self-resistant elements BlmB and TlmB, discovered from the BLM- and TLM-producing organisms Streptomyces verticillus ATCC15...
में बचाया:
में प्रकाशित: | Biochemistry |
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मुख्य लेखकों: | , , , , , , , , |
स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
American
Chemical Society
2014
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ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4230324/ https://ncbi.nlm.nih.gov/pubmed/25299801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi501121e |
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