Resultados da pesquisa - ((((gum j) OR (kuo c))) OR (((eun ju) OR (eun jung)))) ((med chem) OR (red child))

Pesquisas alternativas:
red child » bred child (Expandir a Pesquisa), red chili (Expandir a Pesquisa), fed child (Expandir a Pesquisa)
eun jung » eun young (Expandir a Pesquisa), hyun jung (Expandir a Pesquisa)
gum j » gum _ (Expandir a Pesquisa), lum j (Expandir a Pesquisa)

1

Synthesis and SAR of Thiazolylmethylphenyl Glucoside as Novel C-Aryl Glucoside SGLT2 Inhibitors

Synthesis and SAR of Thiazolylmethylphenyl Glucoside as Novel C-Aryl Glucoside SGLT2 Inhibitors

Por Song, Kwang-Seop, Lee, Suk Ho, Kim, Min Ju, Seo, Hee Jeong, Lee, Junwon, Lee, Sung-Han, Jung, Myung Eun, Son, Eun-Jung, Lee, MinWoo, Kim, Jeongmin, Lee, Jinhwa
Publicado em 2010

“...[Image: see text] Novel C-aryl glucoside SGLT2 inhibitors containing the thiazole motif were...”
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2

Use of Ionically Tagged Glycosyl Donors in the Synthesis of Oligosaccharide Libraries

Use of Ionically Tagged Glycosyl Donors in the Synthesis of Oligosaccharide Libraries

Por Kim, Eun Ju, Gray, Gary R.
Publicado em 2009

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3

Tat-DJ-1 inhibits oxidative stress-mediated RINm5F cell death through suppression of NF-κB and MAPK activation

Tat-DJ-1 inhibits oxidative stress-mediated RINm5F cell death through suppression of NF-κB and MAPK activation

Por Jo, Hyo Sang, Cha, Hyun Ju, Kim, Sang Jin, Yeo, Hyeon Ji, Cho, Su Bin, Park, Jung Hwan, Lee, Chi Hern, Yeo, Eun Ji, Choi, Yeon Joo, Eum, Won Sik, Choi, Soo Young
Publicado no Med Chem Res (2016)

“... pancreatic β-cell (RINm5F) death using cell permeable wild-type and mutant-type (C106A) Tat-DJ-1 proteins...”
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4

Non-proteinogenic amino acids in the pThr-2 position of a pentamer peptide that confer high binding affinity for the polo box domain (PBD) of polo-like kinase 1 (Plk1)

Non-proteinogenic amino acids in the pThr-2 position of a pentamer peptide that confer high binding affinity for the polo box domain (PBD) of polo-like kinase 1 (Plk1)

Por Qian, Wen-Jian, Park, Jung-Eun, Lee, Kyung S., Burke, Terrence R.
Publicado em 2012

“... current finding that the isomeric His(N1)-analogue (1c) binds with approximately 50-fold less affinity...”
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5

Effects on Polo-like Kinase 1 Polo-box Domain Binding Affinities of Peptides Incurred by Structural Variation at the Phosphoamino Acid Position

Effects on Polo-like Kinase 1 Polo-box Domain Binding Affinities of Peptides Incurred by Structural Variation at the Phosphoamino Acid Position

Por Qian, Wenjian, Park, Jung-Eun, Liu, Fa, Lee, Kyung S., Burke, Terrence R.
Publicado em 2012

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6

Probing Binding Modes of Small Molecule Inhibitors to the Polo-Box Domain of Human Polo-like Kinase 1

Probing Binding Modes of Small Molecule Inhibitors to the Polo-Box Domain of Human Polo-like Kinase 1

Por Liao, Chenzhong, Park, Jung-Eun, Bang, Jeong K., Nicklaus, Marc C., Lee, Kyung S.
Publicado em 2010

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7

Optimizing Thiadiazole Analogues of Resveratrol vs. Three Chemopreventive Targets

Optimizing Thiadiazole Analogues of Resveratrol vs. Three Chemopreventive Targets

Por Mayhoub, Abdelrahman S., Marler, Laura, Kondratyuk, Tamara, Park, Eun-Jung, Pezzuto, John M., Cushman, Mark
Publicado em 2011

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8

Optimization of Thiazole Analogues of Resveratrol for Induction of NAD(P)H:quinone Reductase 1 (QR1)

Optimization of Thiazole Analogues of Resveratrol for Induction of NAD(P)H:quinone Reductase 1 (QR1)

Por Mayhoub, Abdelrahman S., Marler, Laura, Kondratyuk, Tamara P., Park, Eun-Jung, Pezzuto, John M., Cushman, Mark
Publicado em 2012

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9

Structure-activity relationships and docking studies of synthetic 2-arylindole derivatives determined with aromatase and quinone reductase 1

Structure-activity relationships and docking studies of synthetic 2-arylindole derivatives determined with aromatase and quinone reductase 1

Por Prior, Allan M., Yu, Xufen, Park, Eun-Jung, Kondratyuk, Tamara P., Lin, Yan, Pezzuto, John M., Sun, Dianqing
Publicado no Bioorg Med Chem Lett (2017)

“... preferred binding with the 2-aryl group toward a small hydrophobic pocket within the active site. The C-5...”
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10

Design, synthesis, and biological evaluation of callophycin A and analogues as potential chemopreventive and anticancer agents

Design, synthesis, and biological evaluation of callophycin A and analogues as potential chemopreventive and anticancer agents

Por Shen, Li, Park, Eun-Jung, Kondratyuk, Tamara P., Guendisch, Daniela, Marler, Laura, Pezzuto, John M., Wright, Anthony D., Sun, Dianqing
Publicado em 2011

“...Callophycin A was originally isolated from the red algae Callophycus oppositifolius and shown...”
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11

OGA inhibition by GlcNAc-selenazoline

OGA inhibition by GlcNAc-selenazoline

Por Kim, Eun Ju, Love, Dona C., Darout, Etzer, Abdo, Mohannad, Rempel, Brian, Withers, Stephen G., Rablen, Paul R., Hanover, John A., Knapp, Spencer
Publicado em 2010

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12

Porphyrin Metabolisms in Human Skin Commensal Propionibacterium acnes Bacteria: Potential Application to Monitor Human Radiation Risk

Porphyrin Metabolisms in Human Skin Commensal Propionibacterium acnes Bacteria: Potential Application to Monitor Human Radiation Risk

Por Shu, M., Kuo, S., Wang, Y., Jiang, Y., Liu, Y.-T., Gallo, R.L., Huang, C.-M.
Publicado em 2013

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13

Anti-AIDS Agents 81. Design, Synthesis and Structure-Activity Relationship Study of Betulinic Acid and Moronic Acid Derivatives as Potent HIV Maturation Inhibitors

Anti-AIDS Agents 81. Design, Synthesis and Structure-Activity Relationship Study of Betulinic Acid and Moronic Acid Derivatives as Potent HIV Maturation Inhibitors

Por Qian, Keduo, Kuo, Reen-Yun, Chen, Chin-Ho, Huang, Li, Morris-Natschke, Susan L., Lee, Kuo-Hsiung
Publicado em 2010

“...In our continuing study of triterpene derivatives as potent anti-HIV agents, different C-3...”
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14

Selective Synthesis and Biological Evaluation of Sulfate-Conjugated Resveratrol Metabolites

Selective Synthesis and Biological Evaluation of Sulfate-Conjugated Resveratrol Metabolites

Por Hoshino, Juma, Park, Eun-Jung, Kondratyuk, Tamara P., Marler, Laura, Pezzuto, John M., van Breemen, Richard B., Mo, Shunyan, Li, Yongchao, Cushman, Mark
Publicado em 2010

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15

Poly[3,4-ethylene dioxythiophene (EDOT) –co– 1,3,5-tri[2-(3,4-ethylene dioxythienyl)]-benzene (EPh)] copolymers (PEDOT-co-EPh): optical, electrochemical and mechanical properties

Poly[3,4-ethylene dioxythiophene (EDOT) –co– 1,3,5-tri[2-(3,4-ethylene dioxythienyl)]-benzene (EPh)] copolymers (PEDOT-co-EPh): optical, electrochemical and mechanical properties...

Por Ouyang, Liangqi, Kuo, Chin-chen, Farrell, Brendan, Pathak, Sheevangi, Wei, Bin, Qu, Jing, Martin, David C.
Publicado no J Mater Chem B Mater Biol Med (2015)

“... of the copolymers changed from blue to yellow to red due to decreased absorption in the near infrared (IR) spectrum...”
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16

Potential Chemopreventive Agents Based on the Structure of the Lead Compound 2-Bromo-1-hydroxyphenazine, Isolated from Streptomyces sp., Strain CNS284

Potential Chemopreventive Agents Based on the Structure of the Lead Compound 2-Bromo-1-hydroxyphenazine, Isolated from Streptomyces sp., Strain CNS284

Por Conda-Sheridan, Martin, Marler, Laura, Park, Eun-Jung, Kondratyuk, Tamara P., Jermihov, Katherine, Mesecar, Andrew D., Pezzuto, John M., Asolkar, Ratnakar N., Fenical, William, Cushman, Mark
Publicado em 2010

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17

Identification, Synthesis, and Biological Evaluation of the Metabolites of 3-Amino-6-(3'-aminopropyl)-5H-indeno[1,2-c]isoquinoline-5,11-(6H)dione (AM6-36), a Promising Rexinoid Lead Compound for the Development of Cancer Chemotherapeutic and Chemopreventive Agents

Identification, Synthesis, and Biological Evaluation of the Metabolites of 3-Amino-6-(3'-aminopropyl)-5H-indeno[1,2-c]isoquinoline-5,11-(6H)dione (AM6-36), a Promising Rexinoid Lead Compound...

Por Chen, Lian, Conda-Sheridan, Martin, Narasimha Reddy, P. V., Morrell, Andrew, Park, Eun-Jung, Kondratyuk, Tamara P., Pezzuto, John M., van Breemen, Richard B., Cushman, Mark
Publicado em 2012

“...'-aminopropyl)-5H-indeno[1,2-c]isoquinoline-5,11-(6H)dione (AM6-36) (3) is among the few RXR ligands known...”
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18

Anti-AIDS Agents 90. Novel C-28 Modified Bevirimat Analogs as Potent HIV Maturation Inhibitors

Anti-AIDS Agents 90. Novel C-28 Modified Bevirimat Analogs as Potent HIV Maturation Inhibitors

Por Qian, Keduo, Bori, Ibrahim D., Chen, Chin-Ho, Huang, Li, Lee, Kuo-Hsiung
Publicado em 2012

“... betulinic acid (BA, 1) derivatives were designed and synthesized. Among these compounds, 17, with a C-28 MEM...”
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19

Antitumor Agents 259. Design, Syntheses and Structure-Activity-Relationship Study of Desmosdumotin C Analogs

Antitumor Agents 259. Design, Syntheses and Structure-Activity-Relationship Study of Desmosdumotin C Analogs

Por Nakagawa-Goto, Kyoko, Chen, Tzu-Hsuan, Peng, Chieh-Yu, Bastow, Kenneth F., Lee, Kuo-Hsiung
Publicado em 2007

“...Desmosdumotin C (1) and its analogs previously showed potent, selective in vitro anticancer...”
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20

A POTENT AND SELECTIVE INHIBITOR TARGETING HUMAN AND MURINE 12/15-LOX

A POTENT AND SELECTIVE INHIBITOR TARGETING HUMAN AND MURINE 12/15-LOX

Por Armstrong, Michelle M., Freedman, Cody J., Jung, Joo Eun, Zheng, Yi, Kalyanaraman, Chakrapani, Jacobson, Matthew P., Simeonov, Anton, Maloney, David J., van Leyen, Klaus, Jadhav, Ajit, Holman, Theodore R.
Publicado no Bioorg Med Chem (2016)

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