New series of monoquaternary pyridinium oximes: synthesis and reactivation potency for paraoxon-inhibited electric eel and recombinant human acetylcholinesterase

Por Bharate, Sandip B., Guo, Lilu, Reeves, Tony E., Cerasoli, Douglas M., Thompson, Charles M.
Publicado em 2009

INHIBITION OF ACETYLCHOLINESTERASE BY CHROMOPHORE-LINKED FLUOROPHOSPHONATES

Por Guo, Lilu, Suarez, Alirica I., Braden, Michael R., Gerdes, John M., Thompson, Charles M.
Publicado em 2009

Design, synthesis and SAR exploration of tri-substituted 1,2,4-triazoles as inhibitors of the annexin A2–S100A10 protein interaction

Por Reddy, Tummala R.K., Li, Chan, Guo, Xiaoxia, Fischer, Peter M., Dekker, Lodewijk V.
Publicado em 2014

Novel 2- and 4- Substituted 1H-Imidazo[4,5-c]quinolin-4-amine Derivatives as Allosteric Modulators of the A(3) Adenosine Receptor

Por Kim, Yoonkyung, de Castro, Sonia, Gao, Zhan-Guo, IJzerman, Adriaan P., Jacobson, Kenneth A.
Publicado em 2009

MODELING IN VITRO INHIBITION OF BUTYRYLCHOLINESTERASE USING MOLECULAR DOCKING, MULTI-LINEAR REGRESSION AND ARTIFICIAL NEURAL NETWORK APPROACHES

Por Zheng, Fang, Zhan, Max, Huang, Xiaoqin, AbdulHameed, Mohamed Diwan M., Zhan, Chang-Guo
Publicado em 2013

Bisquaternary pyridinium oximes: Comparison of in-vitro reactivation potency of compounds bearing aliphatic linkers and heteroaromatic linkers for paraoxon-inhibited electric eel a...

Por Bharate, Sandip B., Guo, Lilu, Reeves, Tony E., Cerasoli, Douglas M., Thompson, Charles M.
Publicado em 2009

A multifunctional poly(curcumin) nanomedicine for dual-modal targeted delivery, intracellular responsive release, dual-drug treatment and imaging of multidrug resistant cancer cell...

Por Wang, Jining, Wang, Feihu, Li, Fangzhou, Zhang, Wenjun, Shen, Yuanyuan, Zhou, Dejian, Guo, Shengrong
Publicado no J Mater Chem B Mater Biol Med (2016)

Human P2Y(1) Receptor: Molecular Modeling and Site-Directed Mutagenesis as Tools To Identify Agonist and Antagonist Recognition Sites

Por Moro, Stefano, Guo, Danping, Camaioni, Emidio, Boyer, José L., Harden, T. Kendall, Jacobson, Kenneth A.
Publicado em 1998

Identification of a Potent New Chemotype for the Selective Inhibition of PDE4

Por Skoumbourdis, Amanda P., Huang, Ruili, Southall, Noel, Leister, William, Guo, Vicky, Cho, Ming-Hsuang, Inglese, James, Nirenberg, Marshall, Austin, Christopher P., Xia, Menghang, Thomas, Craig J.
Publicado em 2008

Synthesis and structure–activity relationship studies of tyrosine-based antagonists at the human P2X(7) receptor

Por Lee, Ga Eun, Joshi, Bhalchandra V., Chen, Wangzhong, Jeong, Lak Shin, Moon, Hyung Ryong, Jacobson, Kenneth A., Kim, Yong-Chul
Publicado em 2007

Design, synthesis, and biological evaluation of callophycin A and analogues as potential chemopreventive and anticancer agents

Por Shen, Li, Park, Eun-Jung, Kondratyuk, Tamara P., Guendisch, Daniela, Marler, Laura, Pezzuto, John M., Wright, Anthony D., Sun, Dianqing
Publicado em 2011

Design, Synthesis, and Biological Evaluation of Indenoisoquinoline Rexinoids with Chemopreventive Potential

Por Conda-Sheridan, Martin, Park, Eun-Jung, Beck, Daniel E., Narasimha Reddy, P. V., Nguyen, Trung X., Hu, Bingjie, Chen, Lian, White, Jerry J., van Breemen, Richard B., Pezzuto, John M., Cushman, Mark
Publicado em 2013

Syntheses of novel high affinity ligands for opioid receptors

Por Wentland, Mark P., Lou, Rongliang, Lu, Qun, Bu, Yigong, Denhardt, Christoph, Jin, Jin, Ganorkar, Rakesh, VanAlstine, Melissa A., Guo, Chengyun, Cohen, Dana J., Bidlack, Jean M.
Publicado em 2009

Himbacine-Derived Thrombin Receptor Antagonists: C(7)-Spirocyclic Analogues of Vorapaxar

Por Chelliah, Mariappan V., Eagen, Keith, Guo, Zhuyan, Chackalamannil, Samuel, Xia, Yan, Tsai, Hsingan, Greenlee, William J., Ahn, Ho-Sam, Kurowski, Stan, Boykow, George, Hsieh, Yunsheng, Chintala, Madhu
Publicado em 2014

Natural products and morphogenic activity of γ-Proteobacteria associated with the marine hydroid polyp Hydractinia echinata

Por Guo, Huijuan, Rischer, Maja, Sperfeld, Martin, Weigel, Christiane, Menzel, Klaus Dieter, Clardy, Jon, Beemelmanns, Christine
Publicado no Bioorg Med Chem (2017)

Magnetically Aligned Bicelles to Study the Orientation of Lipophilic Ligands in Membrane Bilayers

Por Guo, Jianxin, Yang, De-Ping, Chari, Ravi, Tian, Xiaoyu, Pavlopoulos, Spiro, Lu, Dai, Makriyannis, Alexandros
Publicado em 2008

Conformationally constrained analogues of 2-arachidonoylglycerol

Por Vadivel, Subramanian K., Vardarajan, Sundararaman, Duclos, Richard I., Wood, JodiAnne T., Guo, Jianxin, Makriyannis, Alexandros
Publicado em 2007

2,4-Diamino-5-methyl-6-substituted Arylthio-furo[2,3-d]pyrimidines as Novel Classical and Nonclassical Antifolates as Potential Dual Thymidylate Synthase and Dihydrofolate Reductas...

Por Gangjee, Aleem, Jain, Hiteshkumar D., Phan, Jaclyn, Guo, Xin, Queener, Sherry F., Kisliuk, Roy L.
Publicado em 2009

Structure-Based Scaffold Repurposing for G Protein-Coupled Receptors: Transformation of Adenosine Derivatives into 5HT(2B)/5HT(2C) Serotonin Receptor Antagonists

Por Tosh, Dilip K., Ciancetta, Antonella, Warnick, Eugene, Crane, Steven, Gao, Zhan-Guo, Jacobson, Kenneth A.
Publicado no J Med Chem (2016)

Analysis of nine compounds from Alpinia oxyphylla fruit at different harvest time using UFLC-MS/MS and an extraction method optimized by orthogonal design

Por Li, Yong-Hui, Chen, Feng, Wang, Jun-fang, Wang, Yong, Zhang, Jun-Qing, Guo, Tao
Publicado em 2013