Resultados da pesquisa - "hdv"

41

IFITM3 Interacts with the HBV/HDV Receptor NTCP and Modulates Virus Entry and Infection

IFITM3 Interacts with the HBV/HDV Receptor NTCP and Modulates Virus Entry and Infection

Por Massimo Palatini, Simon Franz Müller, Michael Kirstgen, Silke Leiting, Felix Lehmann, Lena Soppa, Nora Goldmann, Christin Müller, Kira Alessandra Alicia Theresa Lowjaga, Jörg Alber, Giuliano Ciarimboli, John Ziebuhr, Dieter Glebe, Joachim Geyer
Publicado em 2022-03-01

Assuntos: “...HDV...”
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42

Folding of the HDV antigenomic ribozyme pseudoknot structure deduced from long-range photocrosslinks.

Folding of the HDV antigenomic ribozyme pseudoknot structure deduced from long-range photocrosslinks.

Por Bravo, C, Lescure, F, Laugâa, P, Fourrey, J L, Favre, A
Publicado em 1996

“... of the anti-genomic HDV ribozyme. In this system, the substrate (SANT) is associated by base-pairing...”
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43

Self-cleavage activity of the genomic HDV ribozyme in the presence of various divalent metal ions.

Self-cleavage activity of the genomic HDV ribozyme in the presence of various divalent metal ions.

Por Suh, Y A, Kumar, P K, Taira, K, Nishikawa, S
Publicado em 1993

“... ribozyme of human hepatitis delta virus (HDV), we tested the activity of various divalent metal ions...”
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44

Metal Binding Motif in the Active Site of the HDV Ribozyme Binds Divalent and Monovalent Ions

Metal Binding Motif in the Active Site of the HDV Ribozyme Binds Divalent and Monovalent Ions

Por Veeraraghavan, Narayanan, Ganguly, Abir, Chen, Jui-Hui, Bevilacqua, Philip C., Hammes-Schiffer, Sharon, Golden, Barbara L.
Publicado em 2011

“...The hepatitis delta virus (HDV) ribozyme uses both metal ion and nucleobase catalysis in its...”
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45

Phylogenetic analysis of HDV isolates from HBsAg positive patients in Karachi, Pakistan

Phylogenetic analysis of HDV isolates from HBsAg positive patients in Karachi, Pakistan

Por Perveen, Shadab, Nasir, Muhammad Israr, Shahid, Syed M, Azhar, Abid, Khan, Obaid Yusuf
Publicado em 2012

“..., no genetic study of Hepatitis Delta virus (HDV) isolates from this region was carried out. The aim...”
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46

Standard and pegylated interferon therapy of HDV infection: A systematic review and meta- analysis

Standard and pegylated interferon therapy of HDV infection: A systematic review and meta- analysis

Por Alavian, Seyed-Moayed, Tabatabaei, Seyed Vahid, Behnava, Bita, Rizzetto, Mario
Publicado em 2012

“...BACKGROUND: Hepatitis D virus (HDV) infection is characterized by rapidly progressive liver disease...”
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47

New tools provide a second look at HDV ribozyme structure, dynamics and cleavage

New tools provide a second look at HDV ribozyme structure, dynamics and cleavage

Por Kapral, Gary J., Jain, Swati, Noeske, Jonas, Doudna, Jennifer A., Richardson, David C., Richardson, Jane S.
Publicado no Nucleic Acids Res (2014)

“...The hepatitis delta virus (HDV) ribozyme is a self-cleaving RNA enzyme essential for processing...”
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48

Wobble Pairs of the HDV Ribozyme Play Specific Roles in Stabilization of Active Site Dynamics

Wobble Pairs of the HDV Ribozyme Play Specific Roles in Stabilization of Active Site Dynamics

Por Sripathi, Kamali N., Banáš, Pavel, Reblova, Kamila, Šponer, Jiři, Otyepka, Michal, Walter, Nils G.
Publicado no Phys Chem Chem Phys (2015)

“...The hepatitis delta virus (HDV) is the only known human pathogen whose genome contains a catalytic...”
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49

A Two-Metal-Ion-Mediated Conformational Switching Pathway for HDV Ribozyme Activation

A Two-Metal-Ion-Mediated Conformational Switching Pathway for HDV Ribozyme Activation

Por Lee, Tai-Sung, Radak, Brian K., Harris, Michael E., York, Darrin M.
Publicado no ACS Catal (2016)

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50

Deletion of internal sequence on the HDV-ribozyme: elucidation of functionally important single-stranded loop regions.

Deletion of internal sequence on the HDV-ribozyme: elucidation of functionally important single-stranded loop regions.

Por Suh, Y A, Kumar, P K, Nishikawa, F, Kayano, E, Nakai, S, Odai, O, Uesugi, S, Taira, K, Nishikawa, S
Publicado em 1992

“... in genomic hepatitis delta virus (HDV) ribozyme possessing self-cleavage activity, we have constructed...”
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51

Unbiased in vitro selection reveals the unique character of the self-cleaving antigenomic HDV RNA sequence

Unbiased in vitro selection reveals the unique character of the self-cleaving antigenomic HDV RNA sequence

Por Nehdi, Atef, Perreault, Jean-Pierre
Publicado em 2006

“... virus (HDV) ribozyme we developed an unbiased in vitro selection procedure that efficiently selected...”
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52

Chemical rescue, multiple ionizable groups, and general acid–base catalysis in the HDV genomic ribozyme

Chemical rescue, multiple ionizable groups, and general acid–base catalysis in the HDV genomic ribozyme

Por Perrotta, Anne T., Wadkins, Timothy S., Been, Michael D.
Publicado em 2006

“...In the ribozyme from the hepatitis delta virus (HDV) genomic strand RNA, a cytosine side chain...”
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53

A catalytic metal ion interacts with the cleavage site G•U wobble in the HDV ribozyme

A catalytic metal ion interacts with the cleavage site G•U wobble in the HDV ribozyme

Por Chen, Jui-Hui, Gong, Bo, Bevilacqua, Philip C., Carey, Paul R., Golden, Barbara L.
Publicado em 2009

“...The HDV ribozyme self-cleaves by a chemical mechanism involving general acid-base catalysis...”
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54

Mechanistic Strategies in the HDV Ribozyme: Chelated and Diffuse Metal Ion Interactions and Active Site Protonation

Mechanistic Strategies in the HDV Ribozyme: Chelated and Diffuse Metal Ion Interactions and Active Site Protonation

Por Veeraraghavan, Narayanan, Ganguly, Abir, Golden, Barbara L., Bevilacqua, Philip C., Hammes-Schiffer, Sharon
Publicado em 2011

“...The crystal structure of the precleaved form of the hepatitis delta virus (HDV) ribozyme reveals...”
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55

Quantum Mechanical/Molecular Mechanical Study of the HDV Ribozyme: Impact of the Catalytic Metal Ion on the Mechanism

Quantum Mechanical/Molecular Mechanical Study of the HDV Ribozyme: Impact of the Catalytic Metal Ion on the Mechanism

Por Ganguly, Abir, Bevilacqua, Philip C., Hammes-Schiffer, Sharon
Publicado em 2011

“...A recent crystal structure of the precleaved HDV ribozyme along with biochemical data support a...”
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56

HDV+HBV hepatitis reactivation due to immunossuppressive therapy for hematological malignancies – an increasingly complex challenge

HDV+HBV hepatitis reactivation due to immunossuppressive therapy for hematological malignancies – an increasingly complex challenge

Por Molagic, Violeta, Mihăilescu, Raluca, Popescu, Cristina, Tilişcan, Cătălin, Rădulescu, Mihaela, Năstase, Raluca, Moroti, Ruxandra, Poghirc, Viorica, Aramă, Victoria
Publicado em 2013

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57

Disparate HDV ribozyme crystal structures represent intermediates on a rugged free-energy landscape

Disparate HDV ribozyme crystal structures represent intermediates on a rugged free-energy landscape

Por Sripathi, Kamali N., Tay, Wendy W., Banáš, Pavel, Otyepka, Michal, Šponer, Jiří, Walter, Nils G.
Publicado em 2014

“...The hepatitis delta virus (HDV) ribozyme is a member of the class of small, self-cleaving catalytic...”
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58

Transition State Features in the Hepatitis Delta Virus (HDV) Ribozyme Reaction Revealed by Atomic Perturbations

Transition State Features in the Hepatitis Delta Virus (HDV) Ribozyme Reaction Revealed by Atomic Perturbations

Por Koo, Selene C., Lu, Jun, Li, Nan-Sheng, Leung, Edward, Das, Subha R., Harris, Michael E., Piccirilli, Joseph A.
Publicado no J Am Chem Soc (2015)

“... relating functional data to the physically observed RNA architecture. In the case of the HDV ribozyme...”
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59

Topological constraints of structural elements in regulation of catalytic activity in HDV-like self-cleaving ribozymes

Topological constraints of structural elements in regulation of catalytic activity in HDV-like self-cleaving ribozymes

Por Webb, Chiu-Ho T., Nguyen, Dang, Myszka, Marie, Lupták, Andrej
Publicado no Sci Rep (2016)

“... (HDV)-like ribozymes are activated by peripheral domains that bring two helical segments, P1 and P2...”
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60

Core sequences and a cleavage site wobble pair required for HDV antigenomic ribozyme self-cleavage.

Core sequences and a cleavage site wobble pair required for HDV antigenomic ribozyme self-cleavage.

Por Perrotta, A T, Been, M D
Publicado em 1996

“...The secondary structures proposed for the cis-acting hepatitis delta virus (HDV) ribozymes contain...”
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