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Disparate HDV ribozyme crystal structures represent intermediates on a rugged free-energy landscape
The hepatitis delta virus (HDV) ribozyme is a member of the class of small, self-cleaving catalytic RNAs found in a wide range of genomes from HDV to human. Both pre- and post-catalysis (precursor and product) crystal structures of the cis-acting genomic HDV ribozyme have been determined. These stru...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4114689/ https://ncbi.nlm.nih.gov/pubmed/24854621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.044982.114 |
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