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Chemical Feasibility of the General Acid/Base Mechanism of glmS Ribozyme Self-Cleavage
In numerous Gram-positive bacteria, the glmS ribozyme or catalytic riboswitch regulates the expression of glucosamine-6-phosphate (GlcN6P) synthase via site-specific cleavage of its sugar-phosphate backbone in response to GlcN6P ligand binding. Biochemical data have suggested a crucial catalytic rol...
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| Gepubliceerd in: | Biopolymers |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4553064/ https://ncbi.nlm.nih.gov/pubmed/25858644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.22657 |
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