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Chemical Feasibility of the General Acid/Base Mechanism of glmS Ribozyme Self-Cleavage

In numerous Gram-positive bacteria, the glmS ribozyme or catalytic riboswitch regulates the expression of glucosamine-6-phosphate (GlcN6P) synthase via site-specific cleavage of its sugar-phosphate backbone in response to GlcN6P ligand binding. Biochemical data have suggested a crucial catalytic rol...

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Bibliografiska uppgifter
I publikationen:Biopolymers
Huvudupphovsmän: Dubecký, Matúš, Walter, Nils G., Šponer, Jiří, Otyepka, Michal, Banáš, Pavel
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4553064/
https://ncbi.nlm.nih.gov/pubmed/25858644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.22657
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