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Protonation states of the key active site residues and structural dynamics of glmS riboswitch as reveled by molecular dynamics
The glmS catalytic riboswitch is part of the 5'-untranslated region of mRNAs encoding glucosamine-6-phosphate (GlcN6P) synthetase (glmS) in numerous Gram-positive bacteria. Binding of the cofactor GlcN6P induces site-specific self-cleavage of the RNA. However, detailed reaction mechanism as wel...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2900856/ https://ncbi.nlm.nih.gov/pubmed/20536206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp9109699 |
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