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Molecular Mechanism of preQ(1) Riboswitch Action: A Molecular Dynamics Study
Riboswitches often occur in the 5’-untranslated regions of bacterial mRNA where they regulate gene expression. The preQ(1) riboswitch controls the biosynthesis of a hypermodified nucleoside queuosine in response to binding the queuosine metabolic intermediate. Structures of the ligand-bound and liga...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3505677/ https://ncbi.nlm.nih.gov/pubmed/22998634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp309230v |
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