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Molecular Mechanism of preQ(1) Riboswitch Action: A Molecular Dynamics Study

Riboswitches often occur in the 5’-untranslated regions of bacterial mRNA where they regulate gene expression. The preQ(1) riboswitch controls the biosynthesis of a hypermodified nucleoside queuosine in response to binding the queuosine metabolic intermediate. Structures of the ligand-bound and liga...

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Main Authors: Banáš, Pavel, Sklenovský, Petr, Wedekind, Joseph E., Šponer, Jiří, Otyepka, Michal
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3505677/
https://ncbi.nlm.nih.gov/pubmed/22998634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp309230v
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