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Unbiased in vitro selection reveals the unique character of the self-cleaving antigenomic HDV RNA sequence

In order to revisit the architecture of the catalytic center of the antigenomic hepatitis delta virus (HDV) ribozyme we developed an unbiased in vitro selection procedure that efficiently selected novel variants from a relatively small set of sequences. Using this procedure we examined all possible...

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Detalhes bibliográficos
Main Authors: Nehdi, Atef, Perreault, Jean-Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1345697/
https://ncbi.nlm.nih.gov/pubmed/16432262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkj463
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