New tools provide a second look at HDV ribozyme structure, dynamics and cleavage

The hepatitis delta virus (HDV) ribozyme is a self-cleaving RNA enzyme essential for processing viral transcripts during rolling circle viral replication. The first crystal structure of the cleaved ribozyme was solved in 1998, followed by structures of uncleaved, mutant-inhibited and ion-complexed f...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Kapral, Gary J., Jain, Swati, Noeske, Jonas, Doudna, Jennifer A., Richardson, David C., Richardson, Jane S.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
RNA
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227795/
https://ncbi.nlm.nih.gov/pubmed/25326328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku992
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