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The poly(A) site sequence in HDV RNA alters both extent and rate of self-cleavage of the antigenomic ribozyme

The ribozyme self-cleavage site in the antigenomic sequence of hepatitis delta virus (HDV) RNA is 33-nt downstream of the poly(A) site for the delta antigen mRNA. An HDV antigenomic ribozyme precursor RNA that included the upstream poly(A) processing site was used to test the hypothesis that nonribo...

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Detalhes bibliográficos
Main Authors: Brown, Abigail L., Perrotta, Anne T., Wadkins, Timothy S., Been, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396440/
https://ncbi.nlm.nih.gov/pubmed/18388129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn156
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