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The poly(A) site sequence in HDV RNA alters both extent and rate of self-cleavage of the antigenomic ribozyme

The ribozyme self-cleavage site in the antigenomic sequence of hepatitis delta virus (HDV) RNA is 33-nt downstream of the poly(A) site for the delta antigen mRNA. An HDV antigenomic ribozyme precursor RNA that included the upstream poly(A) processing site was used to test the hypothesis that nonribo...

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Detalles Bibliográficos
Main Authors: Brown, Abigail L., Perrotta, Anne T., Wadkins, Timothy S., Been, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2008
Assuntos:
RNA
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396440/
https://ncbi.nlm.nih.gov/pubmed/18388129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn156
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