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The poly(A) site sequence in HDV RNA alters both extent and rate of self-cleavage of the antigenomic ribozyme

The ribozyme self-cleavage site in the antigenomic sequence of hepatitis delta virus (HDV) RNA is 33-nt downstream of the poly(A) site for the delta antigen mRNA. An HDV antigenomic ribozyme precursor RNA that included the upstream poly(A) processing site was used to test the hypothesis that nonribo...

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Hlavní autoři: Brown, Abigail L., Perrotta, Anne T., Wadkins, Timothy S., Been, Michael D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2008
Témata:
RNA
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396440/
https://ncbi.nlm.nih.gov/pubmed/18388129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn156
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