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Topological constraints of structural elements in regulation of catalytic activity in HDV-like self-cleaving ribozymes

Self-cleaving ribozymes fold into intricate structures, which orient active site groups into catalytically competent conformations. Most ribozyme families have distinct catalytic cores stabilized by tertiary interactions between domains peripheral to those cores. We show that large hepatitis delta v...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Webb, Chiu-Ho T., Nguyen, Dang, Myszka, Marie, Lupták, Andrej
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908430/
https://ncbi.nlm.nih.gov/pubmed/27302490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28179
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