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Chemistry and biology of self-cleaving ribozymes

Self-cleaving ribozymes were discovered thirty years ago, but their biological distribution and catalytic mechanisms are only beginning to be defined. Each ribozyme family is defined by a distinct structure with unique active sites accelerating the same transesterification reaction across the famili...

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Bibliographic Details
Published in:Trends Biochem Sci
Main Authors: Jimenez, Randi M., Polanco, Julio A., Lupták, Andrej
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4630146/
https://ncbi.nlm.nih.gov/pubmed/26481500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2015.09.001
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