טוען...
Xist-dependent imprinted X inactivation and the early developmental consequences of its failure
The long non-coding RNA Xist is only expressed from the paternal X chromosome in mouse pre-implantation female embryos and leads to its transcriptional silencing. In females, absence of Xist leads to post-implantation lethality. Here we report that the initiation of imprinted XCI absolutely requires...
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| הוצא לאור ב: | Nat Struct Mol Biol |
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| Main Authors: | , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2017
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5337400/ https://ncbi.nlm.nih.gov/pubmed/28134930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3365 |
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