The bipartite TAD organization of the X-inactivation center ensures opposing developmental regulation of Tsix and Xist

The mouse X-inactivation center (Xic) locus represents a powerful model for understanding the links between genome architecture and gene regulation, with the non-coding genes Xist and Tsix showing opposite developmental expression patterns while being organized as an overlapping sense/antisense unit...

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Bibliografiska uppgifter
I publikationen:Nat Genet
Huvudupphovsmän: van Bemmel, Joke G., Galupa, Rafael, Gard, Chris, Servant, Nicolas, Picard, Christel, Davies, James, Szempruch, Anthony James, Zhan, Yinxiu, Żylicz, Jan J., Nora, Elphège P., Lameiras, Sonia, de Wit, Elzo, Gentien, David, Baulande, Sylvain, Giorgetti, Luca, Guttman, Mitchell, Hughes, Jim R., Higgs, Douglas R., Gribnau, Joost, Heard, Edith
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6551226/
https://ncbi.nlm.nih.gov/pubmed/31133748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-019-0412-0
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