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A Conserved Noncoding Locus Regulates Random Monoallelic Xist Expression across a Topological Boundary
cis-Regulatory communication is crucial in mammalian development and is thought to be restricted by the spatial partitioning of the genome in topologically associating domains (TADs). Here, we discovered that the Xist locus is regulated by sequences in the neighboring TAD. In particular, the promote...
שמור ב:
| הוצא לאור ב: | Mol Cell |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Cell Press
2020
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| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6964159/ https://ncbi.nlm.nih.gov/pubmed/31759823 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.10.030 |
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