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Synergy of Eed and Tsix in the repression of Xist gene and X-chromosome inactivation
X-chromosome inactivation (XCI) depends on the noncoding Xist gene. Xist transcription is negatively regulated by its antisense partner Tsix, whose disruption results in nonrandom XCI in females. However, males can maintain Xist in a repressed state without Tsix, indicating participation of addition...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2008
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2486422/ https://ncbi.nlm.nih.gov/pubmed/18511907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.110 |
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