Histone H3 Lysine 36 Trimethylation Is Established over the Xist Promoter by Antisense Tsix Transcription and Contributes to Repressing Xist Expression

One of the two X chromosomes in female mammals is inactivated by the noncoding Xist RNA. In mice, X chromosome inactivation (XCI) is regulated by the antisense RNA Tsix, which represses Xist on the active X chromosome. In the absence of Tsix, PRC2-mediated histone H3 lysine 27 trimethylation (H3K27m...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Ohhata, Tatsuya, Matsumoto, Mika, Leeb, Martin, Shibata, Shinwa, Sakai, Satoshi, Kitagawa, Kyoko, Niida, Hiroyuki, Kitagawa, Masatoshi, Wutz, Anton
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609750/
https://ncbi.nlm.nih.gov/pubmed/26370508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00561-15
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