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Lineage-specific function of the noncoding Tsix RNA for Xist repression and Xi reactivation in mice

The noncoding Tsix RNA is an antisense repressor of Xist and regulates X inactivation in mice. Tsix is essential for preventing the inactivation of the maternally inherited X chromosome in extraembryonic lineages where imprinted X-chromosome inactivation (XCI) occurs. Here we establish an inducible...

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Detalhes bibliográficos
Main Authors: Ohhata, Tatsuya, Senner, Claire E., Hemberger, Myriam, Wutz, Anton
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165935/
https://ncbi.nlm.nih.gov/pubmed/21852535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.16997911
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