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Antisense Transcription through the Xist Locus Mediates Tsix Function in Embryonic Stem Cells

Expression of the Xist gene, a key player in mammalian X inactivation, has been proposed to be controlled by the antisense Tsix transcript. Targeted deletion of the Tsix promoter encompassing the DPXas34 locus leads to nonrandom inactivation of the mutant X, but it remains unresolved whether this ph...

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Detalhes bibliográficos
Main Authors: Luikenhuis, Sandra, Wutz, Anton, Jaenisch, Rudolf
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC100014/
https://ncbi.nlm.nih.gov/pubmed/11713286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.24.8512-8520.2001
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