Antisense Transcription through the Xist Locus Mediates Tsix Function in Embryonic Stem Cells

Expression of the Xist gene, a key player in mammalian X inactivation, has been proposed to be controlled by the antisense Tsix transcript. Targeted deletion of the Tsix promoter encompassing the DPXas34 locus leads to nonrandom inactivation of the mutant X, but it remains unresolved whether this ph...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Luikenhuis, Sandra, Wutz, Anton, Jaenisch, Rudolf
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2001
Assuntos:	Transcriptional Regulation
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC100014/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11713286/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.24.8512-8520.2001
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