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Antisense Transcription through the Xist Locus Mediates Tsix Function in Embryonic Stem Cells

Expression of the Xist gene, a key player in mammalian X inactivation, has been proposed to be controlled by the antisense Tsix transcript. Targeted deletion of the Tsix promoter encompassing the DPXas34 locus leads to nonrandom inactivation of the mutant X, but it remains unresolved whether this ph...

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Publicat a:Mol Cell Biol
Autors principals: Luikenhuis, Sandra, Wutz, Anton, Jaenisch, Rudolf
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2001
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC100014/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11713286/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.24.8512-8520.2001
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