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A Chromosomal Memory Triggered by Xist Regulates Histone Methylation in X Inactivation

We have elucidated the kinetics of histone methylation during X inactivation using an inducible Xist expression system in mouse embryonic stem (ES) cells. Previous reports showed that the ability of Xist to trigger silencing is restricted to an early window in ES cell differentiation. Here we show t...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Kohlmaier, Alexander, Savarese, Fabio, Lachner, Monika, Martens, Joost, Jenuwein, Thomas, Wutz, Anton
Formato: Artigo
Idioma:Inglês
Publicado em: PLOS 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC449785/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15252442/
https://ncbi.nlm.nih.govhttps://doi.org/10.1371/journal.pbio.0020171
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