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The bipartite TAD organization of the X-inactivation center ensures opposing developmental regulation of Tsix and Xist

The mouse X-inactivation center (Xic) locus represents a powerful model for understanding the links between genome architecture and gene regulation, with the non-coding genes Xist and Tsix showing opposite developmental expression patterns while being organized as an overlapping sense/antisense unit...

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Detalhes bibliográficos
Publicado no:Nat Genet
Main Authors: van Bemmel, Joke G., Galupa, Rafael, Gard, Chris, Servant, Nicolas, Picard, Christel, Davies, James, Szempruch, Anthony James, Zhan, Yinxiu, Żylicz, Jan J., Nora, Elphège P., Lameiras, Sonia, de Wit, Elzo, Gentien, David, Baulande, Sylvain, Giorgetti, Luca, Guttman, Mitchell, Hughes, Jim R., Higgs, Douglas R., Gribnau, Joost, Heard, Edith
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6551226/
https://ncbi.nlm.nih.gov/pubmed/31133748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-019-0412-0
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