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The bipartite TAD organization of the X-inactivation center ensures opposing developmental regulation of Tsix and Xist

The mouse X-inactivation center (Xic) locus represents a powerful model for understanding the links between genome architecture and gene regulation, with the non-coding genes Xist and Tsix showing opposite developmental expression patterns while being organized as an overlapping sense/antisense unit...

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Bibliografski detalji
Izdano u:Nat Genet
Glavni autori: van Bemmel, Joke G., Galupa, Rafael, Gard, Chris, Servant, Nicolas, Picard, Christel, Davies, James, Szempruch, Anthony James, Zhan, Yinxiu, Żylicz, Jan J., Nora, Elphège P., Lameiras, Sonia, de Wit, Elzo, Gentien, David, Baulande, Sylvain, Giorgetti, Luca, Guttman, Mitchell, Hughes, Jim R., Higgs, Douglas R., Gribnau, Joost, Heard, Edith
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6551226/
https://ncbi.nlm.nih.gov/pubmed/31133748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-019-0412-0
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